Biography
Rachel Byrne is an implementation scientist with a focus on the decentralisation of diagnostic tests for infectious diseases at the point of care and need. Through her research she tries to understand factors that contribute to the success of test uptake in high disease burden countries.
Alongside colleagues at Seoul National University, Rachel is the Co-chair of the computer aided detection access framework group that includes members from the World Health Organisation, Unitaid, Global Fund, StopTB partnership, Stellenbosch University, and Clinton Health Action Initiative.
Research interests
Rachel’s expertise is in the laboratory and field evaluation of diagnostics and their implementation at the point of need for tuberculosis, nontuberculous mycobacteria and One Health pathogens.
She is currently the Diagnostic and Paediatric Lead of the Start4All consortium. Start4All is a global tuberculosis research consortium working across seven high burden countries (Bangladesh, Brazil, Cameroon, Kenya, Malawi, Nigeria and Viet Nam) funded by Unitaid. Start4All aims to implement and evaluate novel combinations of tuberculosis diagnostics delivered at the lowest healthcare level and the community to improve patient important outcomes.
Selected research publications
Comparison of the analytical and clinical sensitivities of 34 rapid antigen tests with prevalent SARS-CoV-2 variants of concern during the COVID-19 pandemic in the UK – Journal: Microbiology spectrum – Published: 7th October 2025
Aetiologies, neuroradiological features, and risk factors for mortality and long-term neurosequelae of febrile coma in Malawian children: a prospective cohort study: a prospective cohort study – Journal: The Lancet Global Health – Published: 21st May 2025
Head-to-head comparison of anterior nares and nasopharyngeal swabs for SARS-CoV-2 antigen detection in a community drive-through test centre in the UK – Journal: BMJ Open Respiratory Research – Published: 22nd March 2025
Optimization of SARS-CoV-2 culture from clinical samples for clinical trial applications – Journal: mSphere – Published: 16th October 2024
Finding the missed millions: innovations to bring tuberculosis diagnosis closer to key populations – Journal: BMC Global and Public Health – Published: 17th May 2024
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